Dementia Prevention Digest

Estrogen-Only HRT Later in Life Linked to Lower Alzheimer's Risk

Estrogen-Only HRT Later in Life Linked to Lower Alzheimer's Risk

Observational study finds women who started estrogen-only hormone therapy around age 70 had 35% lower odds of Alzheimer's pathology at autopsy and 39% lower clinical dementia diagnosis. Adds nuance to hormone-dementia debate, but association not causation. Hopeful signal for prevention.

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Updated Aug 14, 2026