Dementia Prevention Digest

A new self-report tool targets spatial navigation difficulties as an early Alzheimer's signal, often before memory loss appears.

• SPAM...

The FDA cleared PrecivityAD2 as the first blood test for symptomatic adults as young as 40, marking a regulatory milestone for accessible early...

Better multidimensional sleep health strongly predicts lower odds of mild cognitive impairment among older adults.

• Each one-point rise in the...

A novel autologous stem cell therapy, VesCell (ACP-01), is advancing in a Bahamas LARTA trial for vascular cognitive impairment and dementia.

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FDA clearance of PrecivityAD2 gives patients an accessible blood-based option to identify amyloid pathology and guide next steps in care.

• The...

• AI brain age from MRI scans flags dementia risk years early by detecting subtle atrophy missed by standard visual ratings
• Each year a brain...

Emory researchers found that 5,000 IU or more of vitamin D daily was linked to better cognitive scores in adults with sleep disturbance and mild...

Alzheimer’s Association funding has produced a simple blood test measuring amyloid plaques, now available through primary care physicians with...

A clear trend is emerging: Alzheimer's brain changes are detectable far sooner than previously assumed, thanks to advanced MRI and AI.

• Structural...

Structured group programs are reframing dementia prevention for active seniors as actionable rather than inevitable. Neurologist Paul Bendheim...

Blood pressure variability is linked to higher dementia risk, independent of hypertension. This positions fluctuating readings as a distinct, potentially modifiable factor for Alzheimer's prevention.

• CSF test spots Lewy body disease in 10% of symptom-free adults, predicting future Parkinson’s or dementia with Lewy bodies, yet needs invasive...

Two modifiable factors stand out for shifting dementia risk without drugs.

• Hearing loss tops the Lancet’s 2017 list of modifiable risks,...

The field is shifting rapidly from initial disease-slowing medicines and blood tests to targeted gene therapies.

• Approved drugs now slow...

Recurring blood metabolite patterns linked to blood-brain barrier injury could enable non-invasive early detection before neurological symptoms...

A large Swedish registry study of 7,308 people with both Alzheimer's and atrial fibrillation found NOAC users showed modestly slower cognitive...

Compound 10 stops inactive GRK2 from clumping on mitochondria in Alzheimer's mouse models, cutting amyloid beta production, preserving nerve cells,...

New blood biomarkers offer earlier, less invasive Alzheimer's insights, yet misdiagnosis risks and system gaps remain pressing.

• Plasma p-tau217...

Long-term daily use of older antihistamines may raise dementia risk through effects on brain chemistry.

• First-generation drugs like diphenhydramine...

Unexpected behavioral shifts often precede memory loss in dementia, especially in frontotemporal forms.

• Humor flip: Abrupt preference for crude or...