Perimenopause, HRT, testosterone, alcohol, sleep-related symptoms, and endometriosis

Perimenopause is usually assessed clinically rather than through a single hormone panel, and sleep apnea, insomnia, thyroid disease, anemia, medications, restless legs, and mood conditions can mimic or worsen symptoms. Elinzanetant is a potentially relevant nonhormonal vasomotor-symptom treatment, but the available report omitted key trial and safety details, so no new clinical recommendation is warranted.