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OpenFold3 + BioNeMo/Roche: open biomed factories

OpenFold3 + BioNeMo/Roche: open biomed factories

Key Questions

What new genomic foundation models are highlighted?

AlphaGenome, Evo 2, GSFM, Caduceus, DeepVariant, and the new Genos-m model for human-associated microbial genomes are featured.

What is ESMC from BioHub?

ESMC is a protein language model released by BioHub whose details are still pending, noted as a new signal in biomed foundation models.

What limitation remains in open biomed efforts?

A persistent wet-lab verification gap continues to separate computational predictions from experimental validation in these models.

AlphaGenome/Evo 2/GSFM/Caduceus/DeepVariant genomic FMs. New: Genos-m foundation model for human-associated microbial genomes (preprint). New signal: ESMC protein language model from BioHub (details pending). Wet-lab verification gap remains.

Sources (2)
Updated May 30, 2026