High-Dose Opioid Management Digest

Chronic pain emerges only when brain networks merge sensory signals with memory, attention, emotion, and expectation—making it deeply subjective.

Key...

Cychlorphine, appearing in Ohio's illicit street drugs and 10 to 40 times more potent than fentanyl, demands updated overdose protocols because it may...

The Clinical Updates in Pain Medicine 2027 course provides comprehensive training across multiple medical disciplines to enhance pain management and...

A 65-year-old with failed back syndrome and CRPS on 400 MME took her basal opioids before outpatient laparoscopy and received 0.25 mg/kg methadone...

For chronic pain patients, tapering opioids is challenging due to fear of worsening pain, withdrawal symptoms, and deterioration of functioning. Tapering plans must directly address these concerns to succeed.

• Orthopedics drive 6-8% of U.S. opioid prescriptions, with four of five highest-rate surgeries.
• From 2026, Medicare offers separate facility...

Chronic pain patients face healthcare violence through denied medications like Lyrica and medical gaslighting, on top of opioid-crisis scapegoating...

State scope-of-practice limits intersect with federal enforcement to create criminal exposure for nurse practitioners and physician assistants who...

Carisk's new Pain Management Program integrates behavioral health, psychosocial resources, and clinical evaluation to address persistent pain and...

The 2016 CDC guideline's reliance on simplistic MME calculations ignored real pharmacology and genetics, turning rough estimates into rigid policy...

Lynn Watkins told the FDA her psilocybin treatment with facilitated touch and neurorehab let her move her CRPS foot for the first time in nine years,...

True individualized care starts with a full diagnostic evaluation to identify the root cause, not just symptoms.

• Assessment process: Detailed...

• Oklahoma eliminated prior authorization for Brixadi under a value-based agreement, enabling immediate prescribing for SoonerCare members and...

ACCESS launched July 2025 with chronic musculoskeletal pain among four initial tracks, using tech-supported recurring payments tied to...

Former Michigan Rep. Mike Rogers sponsored the 2003 National Pain Care Policy Act to loosen barriers to opioids, backed by industry-funded groups...

Patients taking prescriptions exactly as directed still face lethal risks when no one sees the full medication list.

• Tramadol + antidepressants:...

Intrathecal pain pumps gave OhioHealth patient Marcia Alvarez immediate relief from two decades of back pain, cutting her daily morphine from 40 mg...

The Tele-Pain Program delivers convenient virtual appointments for service members and beneficiaries, connecting them to multidisciplinary services...

This decade-long observational study of 1,000 chronic low-back pain patients on long-term opioids offers direct relevance for high-dose legacy...

• CDC's SUDORS database shows just 1,031 accidental deaths involving only a prescription opioid across 66% of the U.S. population, with rural lab...