Dexamethasone Injection RCT Shows No Benefit for Acute Sciatica

A double-blind randomized trial found caudal dexamethasone no better than saline for disability, pain, quality of life, repeat injections, or surgery in acute sciatica; mild adverse events were more frequent. The findings sharpen uncertainty around epidural steroid injections, although generalization is limited by the acute population and caudal approach.