49ers Lose C.J. West as Three Defensive Linemen Prepare for Season Debuts

C.J. West is on injured reserve after knee surgery, further depleting an interior line that had only three available players against Miami. Viliami Fehoko Jr. and Valdez could make their NFL debuts against Arizona, Kevin Givens is set to return, and Naquan Jones, Gracen Halton and Osa Odighizuwa are expected to absorb major workloads.