Partial Reprogramming Enters Clinics
Key Questions
What is partial reprogramming?
Partial reprogramming uses Yamanaka factors to rewind cells to a more youthful state without causing them to lose their cellular identity. This approach is being developed for anti-aging therapies targeting specific tissues like the brain and eyes.
What is YouthBio's YB002 therapy?
YB002 is YouthBio's treatment for brain cells using partial reprogramming with Yamanaka factors. It has received FDA IND clearance, with first-in-human trials expected soon.
What is Life Biosciences' ER-100?
ER-100 from Life Biosciences applies partial reprogramming via Yamanaka factors for eye-related trials. It aims to rejuvenate cells youthfully while preserving their identity, and is currently in clinical development.
YouthBio's YB002 for brain cells (FDA IND cleared, first-in-human soon) and Life Biosciences' ER-100 (eye trials) use Yamanaka factors to rewind cells youthfully without identity loss.