NFL Week 3 injuries and availability reshape games

Baker Mayfield’s right-thumb dislocation remains the most consequential injury, with an MRI pending and missed time likely. Justin Jefferson’s favorable ankle scan offers optimism, while Mike Evans is out and Trent Williams is questionable; De’Von Achane and Brian Burns are expected to miss the season. Early Week 4 rankings also highlight how injuries and uneven defensive play are shaping Buffalo, Kansas City, San Francisco, Denver, Philadelphia, Cincinnati and Detroit.