Medical Research Compass

Robocath advances precision robotics in cardiovascular care:

• FIH study launched for second-gen system in 20 complex coronary artery disease cases at...

Promising shift for hard-to-treat TNBC: EGFRxHER3 bispecific ADC iza-bren met primary PFS/OS endpoints with statistically significant, clinically...

Pilot trials proposed to bridge NHS gaps for lecanemab and donanemab, slowing early Alzheimer’s.

Key strategies they enable:

• Identify eligible...

Neurodegenerative Diagnostics

• 🔥 Alzheimer’s Blood Test Australia: Australian researchers are advancing blood-based biomarkers for amyloid-beta...

Machine learning harnesses longitudinal data to model individual health trajectories, enabling early disease detection across diverse...

Radiation oncologist Austin Kirschner, MD, endorses the new PROSTOX Standard test for estimating late GU toxicity risk after prostate radiation...

Blood-based biomarkers like amyloid-beta and tau proteins can detect Alzheimer’s years before symptoms, transforming early diagnosis.

• Promising...

Breakthrough in neurosurgery: Adaptive DBS senses brain signals and auto-adjusts stimulation in real-time, unlike traditional DBS.

• Targets:...

Reverse translational research flips the script: routine clinical data now fuels oncology research, drug development, and treatments.

• cNLP...

A young patient's light chains became undetectable within weeks of CAR-T therapy after 15 years of multiple myeloma—including diagnosis during pregnancy, stem cell transplant, and relapses—showcasing breakthrough potential.

Breakthrough plasma biomarker predicts symptomatic Alzheimer's onset using TIRA/SILA models on Knight ADRC/ADNI data.

• Remarkable precision: Median...

Key insights from Dr. Lara Shirikjian, CenExel Medical Director, on patient protection in psych research:

• Operational rigor and protocol mastery...

Recent Delphi survey of 29 practitioners updates MPS II (Hunter syndrome) guidance, last revised in 2003:

• Early ERT strongly favored: 74% before...

ACTRIMS 2026 highlights:

• Brain atrophy as surrogate marker for treatment efficacy in MS clinical trials
• Excitement for FENtrepid trial (NCT04544449) results on fenebrutinib's potential in MS
• Shared by Le Hanh Hua, MD, Cleveland Clinic

First study reveals synergism between PM2.5 and high temperatures on heat-related hospitalization (HRH) risk among elderly Medicare beneficiaries.

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Final PURPOSE trial results at CROI 2026 confirm lenacapavir's superior HIV prevention:

• PURPOSE I (5,300+ cis women, Africa): 0.07/100 ppy incidence...

Targeted funding accelerates breakthroughs for ME/CFS and Long Covid, lacking FDA-approved therapies:

• Semaglutide trial: Prof. Carmen Scheibenbogen...

Cancer Epidemiology & Innovations

• 🔥 Higher Cancer Deaths Near Nuclear Plants: Nationwide analysis reports U.S. counties closer to operating...

• Case study focus: Dr. Alex R. Ario on evolution of Uganda's HIV response via field epidemiology
• CDC YouTube video (24:40 min) details public health strategies
• HIV attacks immune system; untreated leads to AIDS

Key insights from post-COVID antiviral discovery:

• COVID drove thousands of clinical trials targeting SARS-CoV-2 and host proteins.
• Phenotypic...