Seniors polypharmacy: BP overtreatment, OTC/CV/neuro harms, deprescribing
Key Questions
What new label warnings apply to Sivextro?
FDA updated Sivextro labels to warn of serotonin syndrome risk when used with certain drugs. Seniors on multiple medications should monitor symptoms closely.
What bleeding risks are noted for Xarelto?
Xarelto label updates highlight severe bleeding with no antidote available. This is critical for seniors on polypharmacy to discuss deprescribing with doctors.
Why was prazosin recalled for seniors' blood pressure treatment?
Prazosin was recalled due to N-nitroso-prazosin impurity, a potential carcinogen exceeding safe limits. Alternatives should be considered for blood pressure management.
Which medications affect memory in those over 60?
Seven common meds are advised to stop or taper in seniors over 60 due to memory risks, per Beers Criteria updates. Consult checklists for polypharmacy review.
What oral health issue is linked to amlodipine?
Amlodipine, a common blood pressure drug, can cause gum overgrowth. Seniors should monitor dental health and discuss with providers.
FDA label updates: Sivextro serotonin syndrome, Xarelto bleeding no antidote, Xeljanz infections/fractures, Cleocin allergy/ischemia; Ascend atorvastatin dissolution recall; prazosin nitrosamine; 7 meds stop >60 memory; amlodipine gums; Beers OTC ER; NSAIDs heart; neuropathy/foot/B12; Part D/Medicaid. Checklists/doc talks.